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MRI-1 Small Animal Ventilators
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The MRI-1 Ventilator is a small animal ventilator designed for use in MRI and other high magnetic field environments. The system comprises a microprocessor-based control unit and a set of remote, pneumatically operated, non-magnetic valves. The MRI-1 can operate by itself or can be controlled and/or monitored by a computer.
How it works: The MRI-1 operates on the flow-time principle: an inspiratory airflow is established and gated into the animal for a known time, thus producing a known volume. This approach provides extraordinary flexibility — a wide range of volumes, breaths-per-minute, and I/E ratios are possible with no hardware changes, and using just three front-panel controls. For small animals, respiratory airflow is provided by an internal air pump. Alternatively, an external pressurized gas source can be attached (oxygen or anesthetic gasses).
The remote pneumatic valves do the actual airflow switching. By locating these valves close to the animal (including inside the magnet bore if necessary), dead-space and tubing compliance are minimized. A range of valves is now available for animals ranging from mice to pigs. Rodent-size valves are supplied standard, and larger valves can be purchased later as required.
keyword : physiology, respiratory, iitc life science
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