The 5100-Plus is perfect for those who need to keep slices viable for longer e.g. for electrophysiological field recordings. The user can calibrate the Z-axis deflection of the blade to 2 µm with the adjustable blade holder and “Opti-cal” Calibration device. Minimal Z-axis deflection reduces the “chatter” and minimises damage to the slice surface, leading to greater viability of the cells on the slice surface.
keyword : imaging, vibrating microtome, campden instruments ltd