The 5100-Plus is perfect for those who need to keep slices viable for longer e.g. for electrophysiological field recordings. The user can calibrate the Z-axis deflection of the blade to 2 µm with the adjustable blade holder and “Opti-cal” Calibration device. Minimal Z-axis deflection reduces the “chatter” and minimises damage to the slice surface, leading to greater viability of the cells on the slice surface.
This New entry-level Microtome is perfect for techniques such as histology, organotypic slice culture and low resolution imaging with a fixed blade holder and a mechanism Z axis error of ≈ 0µm(±2.0µm).
keyword : electrophysiology, vibrating microtomes, campden instruments ltd